drugset / Trial / NCT07286331

A Study to Investigate Mocertatug Rezetecan Compared With Chemotherapy in Participants With Endometrial Cancer After Platinum-based Chemotherapy and Immunotherapy (BEHOLD-Endometrial01)

NCT07286331

Phase 3 Recruiting 600 enrolled GlaxoSmithKline ENGOT, GOG, APGOT · collab
RandomizedParallel-groupSingle-blindTreatment

Summary

This study specifically aims to evaluate how well mocertatug rezetecan (Mo-Rez) works in treating Endometrial Cancer (EC) compared to standard of care. The study also assesses whether Mo-Rez is safe and tolerated well by participants in comparison to standard of care and will help provide a better understanding of the main side effects of the drugs.

Timeline

Start
2026-06-04
Primary completion
2028-02-29
Completion
2029-05-30

Drugs

EvaluationDrugModalityDoseRoute
Comparator Doxorubicin Other / unclassified
Subject Mocertatug rezetecan Unknown
Comparator Paclitaxel Small molecule

Indications