drugset / Trial / NCT07287956

The Use of Adjunct Oxygen High-Level Laser Therapy on the Clinical and Microbiological Outcomes of Peri-implant Disease

NCT07287956

RandomizedSingle-groupOpen-labelTreatment

Summary

The goal of this clinical trial is to learn whether using a special light-activated treatment called photodynamic therapy, or more specifically, its modified version called oxygen high-level laser therapy, using a high-powered diode laser along with 3% hydrogen peroxide, can improve gum health around dental implants. It tests whether adding this to regular cleaning treatments could reduce harmful bacteria and support better healing. The aim is to determine whether a specific protocol is an effective way to treat infections around dental implants. Participants in the study will receive two types of treatment on different dental implants: * One implant will be treated with the oxygen high-level laser therapy using diode laser and hydrogen peroxide after mechanical cleaning. * The other implant will receive diode laser therapy without hydrogen peroxide after mechanical cleaning. Researchers will compare how the gums respond to each treatment, looking at signs such as inflammation, and determine whether the number of harmful bacteria has been reduced at three time points.

Timeline

Start
2024-02-05
Primary completion
2025-07-07
Completion
2025-08-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Hydrogen Peroxide Small molecule 3 % Other

Indications