drugset / Trial / NCT07291297
Metformin Hydrochloride in Combination With Standard of Care Systemic Therapy in Previously Untreated Advanced Unresectable or Metastatic Soft Tissue Sarcoma
Phase 2
Recruiting
50 enrolled
Wake Forest University Health Sciences
Atrium Health Levine Cancer Institute · collabPaula Takacs Foundation · collab
NaSingle-groupOpen-labelTreatment
Summary
The purpose of this research study is to see how metformin, when used in combination with standard of care (SOC) treatment for metastatic (cancer that has spread) soft tissue sarcoma can improve patient outcomes.
Timeline
- Start
- 2026-03-04
- Primary completion
- 2028-10
- Completion
- 2033-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Metformin | Small molecule | 1000 mg | Oral |