drugset / Trial / NCT07298590

An Exploratory Clinical Study on the Safety and Efficacy of CD19/BCMA CAR-NK in the Treatment of Relapsed and Refractory IgG4-related Disease

NCT07298590

Phase 0 Not yet recruiting 18 enrolled Changhai Hospital
NaSingle-groupOpen-labelTreatment

Summary

A single arm, open-label pilot study is designed to determine the safety and effectiveness of CD19/BCMA CAR NK cells (KN5601) in patients with IgG4 related diseases.

Timeline

Start
2025-12-30
Primary completion
2028-06-26
Completion
2028-12-26

Drugs

EvaluationDrugModalityDoseRoute
Subject CD19/BCMA CAR NK Cell therapy
Background Cyclophosphamide Other / unclassified
Background Fludarabine Small molecule