drugset / Trial / NCT07311408

SHR-1701 + Rivoceranib (± SHR-2554) in Advanced GC After First-Line Immunotherapy Failure

NCT07311408

Phase 2 Recruiting 40 enrolled Jingdong Zhang
RandomizedParallel-groupOpen-labelTreatment

Summary

To investigate the efficacy of SHR-1701 combined with Rivoceranib, with or without SHR-2554, in patients with gastric or gastroesophageal junction adenocarcinoma who have progressed on or were intolerant to first-line immunotherapy-containing treatment

Timeline

Start
2026-01-01
Primary completion
2028-01-01
Completion
2029-12-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Retlirafusp alfa Protein / enzyme biologic Intravenous
Subject Rivoceranib Small molecule Oral
Comparator SHR2554 Small molecule Oral