drugset / Trial / NCT07317414

β-alanine in the Treatment of Advanced Hepatocellular Carcinoma

NCT07317414

Phase 2 Recruiting 158 enrolled Peking Union Medical College Hospital
RandomizedParallel-groupOpen-labelTreatment

Summary

This study is a prospective, randomized controlled study on nutritional support and metabolic regulation. It assesses the safety, compliance, and improvement of metabolic/physical-related indicators when using β-alanine within the specified dose range as dietary supplementation, in addition to the standard first-line treatment. The anti-tumor efficacy (ORR, PFS, OS) is the exploratory endpoint.

Timeline

Start
2025-12-24
Primary completion
2028-12-05
Completion
2030-12-05

Drugs

EvaluationDrugModalityDoseRoute
Subject β- alanine Unknown
Background Atezolizumab Monoclonal antibody
Background Bevacizumab Monoclonal antibody