drugset / Trial / NCT07326371

Glofitamab Combined With CAR-T Therapy in R/R DLBCL

NCT07326371

Phase 2 Not yet recruiting 24 enrolled Ruijin Hospital
NaSingle-groupOpen-labelTreatment

Summary

This study is a single-center, open-label, prospective study aimed at evaluating the efficacy and safety of Glofitamab combined with CAR-T therapy in patients with high-risk relapsed/refractory large B-cell lymphoma.

Timeline

Start
2026-03
Primary completion
2027-07
Completion
2029-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Axicabtagene Ciloleucel Cell therapy Intravenous
Subject Glofitamab Monoclonal antibody Intravenous
Subject Relmacabtagene Autoleucel Cell therapy Intravenous
Background Obinutuzumab Monoclonal antibody 1000 mg Intravenous