drugset / Trial / NCT07341191

Sonrotoclax Plus Zanubrutinib in Patients With Relapsed/Refractory Mantle Cell Lymphoma Planned for Standard of Care CAR-T Cell Therapy

NCT07341191

NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to evaluate the effects of adding two oral medications (sonrotoclax plus zanubrutinib) to standard of care chimeric antigen receptor (CAR-T) cell therapy in participants with mantle cell lymphoma.

Timeline

Start
2026-06-30
Primary completion
2029-12-31
Completion
2030-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Sonrotoclax Other / unclassified Oral
Subject Zanubrutinib Small molecule Oral

Indications