drugset / Trial / NCT07359859
A Study of Ruxolitinib for Preventing Graft-Versus-Host Disease in People With a Hematologic Malignancy Who Will Receive a Stem Cell Transplant
RandomizedParallel-groupOpen-labelPrevention
Summary
The researchers are doing this study to compare 2 different GVHD prevention (prophylaxis) approaches. The researchers will see which approach is good or more effective at preventing chronic GVHD until 1 year after allogeneic hematopoietic stem cell transplantation (allo-HCT).
Timeline
- Start
- 2026-01-20
- Primary completion
- 2029-01
- Completion
- 2029-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Cyclophosphamide | Other / unclassified | — | — |
| Subject | Ruxolitinib | Small molecule | — | — |
| Subject | Tacrolimus | Small molecule | — | — |
| Background | Mycophenolate Mofetil | Small molecule | — | — |