drugset / Trial / NCT07360483
Treatment of Hypertrophic Scars Using Fractional CO2 Laser Alone in Comparison With Adding Botulinum Toxin Either Through Intralesional Injection or Assisted Drug Delivery
RandomizedParallel-groupSingle-blindTreatment
Summary
The current study aimed to evaluate the effectiveness of fractional laser treatment alone and fractional laser combined with botulinum toxin A, delivered either through injections or topical application fractional laser-assisted drug delivery (FLADD) in hypertrophic burn scar
Timeline
- Start
- 2025-01-01
- Primary completion
- 2025-05-01
- Completion
- 2025-08-01
Publications
- Background Tawfik AA, Ali RA. Evaluation of botulinum toxin type A for treating post burn hypertrophic scars and keloid in children: An intra-patient randomized controlled study. J Cosmet Dermatol. 2023 Apr;22(4):1256-1260. doi: 10.1111/jocd.15634. Epub 2023 Jan 31.
- Background Sabry, H.H., Hamed, A.M., & Ibrahim, E.A. (2020). Comparative Study between Intralesional and Topical Botulinum Toxin A Combined with Fractional Carbon Dioxide Laser in Treatment of Hypertrophic Scars and Keloids (Comparative study). Benha Journal of Applied Sciences, 5(3 part (2)), 187-189.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Botulinum toxin type A | Protein / enzyme biologic | 2.5 iu | Other |
Indications
No indication recorded.