drugset / Trial / NCT07374419

Atamparib in Patients With Advanced Solid Tumors

NCT07374419

Phase 1/2 Not yet recruiting 178 enrolled Nerviano Medical Sciences (Shanghai) Ltd.
Non-randomizedSequentialOpen-labelTreatment

Summary

This is a multi-part, open-label, non-randomized phase Ib/II clinical trial designed to evaluate the safety, tolerability, pharmacokinetics, and preliminary antitumor activity of atamparib, an investigational agent, in patients with advanced or metastatic non-small cell lung cancer (NSCLC) adenocarcinoma. The study comprises dose escalation (phase Ib) and expansion (phase II).

Timeline

Start
2026-02-10
Primary completion
2028-07-31
Completion
2029-01-31

Drugs

EvaluationDrugModalityDoseRoute
Subject atamparib Small molecule Oral

Indications