drugset / Trial / NCT07376889

Combination Antibiotic Therapy for Staphylococcus Aureus Bacteremia

NCT07376889 ↗

Phase 4 Recruiting 2096 enrolled Intermountain Health Care, Inc.
RandomizedCrossoverSingle-blindTreatment

Summary

The purpose of this study is to see if, in selected patients with a serious bacterial infection of the bloodstream, treating the bacterial infection with a combination of antibiotics is more effective than treating the infection with a single antibiotic. Participants must have blood cultures which are positive for a certain type of bacteria.

Timeline

Start
2026-02-01
Primary completion
2029-01
Completion
2029-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Cefazolin Small molecule — Intravenous
Subject Ceftaroline Other / unclassified — —
Subject Daptomycin Other / unclassified — —
Subject Ertapenem Small molecule — —
Subject Vancomycin Other / unclassified — —
Subject nafcillin Small molecule — Intravenous