drugset / Trial / NCT07377435

DC/MM Fusion Vaccine With BCMA CAR-T in R/R MM

NCT07377435

Phase 1 Recruiting 25 enrolled David Avigan The V Foundation · collab
NaSingle-groupOpen-labelTreatment

Summary

This study is to evaluate the safety and effectiveness of dendritic cell DC/MM fusion vaccine in combination with standard of care B-cell maturation antigen (BCMA) CAR-T cell therapy in participants with relapsed/refractory multiple myeloma. The names of the study drugs involved in this study are: * DC/MM fusion vaccine (a type of personalized cancer vaccine) * Granulocyte-macrophage colony-stimulating factor (GM-CSF) (a type of growth factor or hormone)

Timeline

Start
2026-01-30
Primary completion
2028-03-01
Completion
2032-03-01

Drugs

EvaluationDrugModalityDoseRoute
Subject DC/MM Fusion Vaccine Vaccine Subcutaneous
Background sargramostim Protein / enzyme biologic Subcutaneous