drugset / Trial / NCT07387666
Imaging Acetadote Metabolism in Glioblastoma
Phase 0
Recruiting
10 enrolled
University of Texas Southwestern Medical Center
Cumberland Pharmaceuticals · collab
NaSingle-groupOpen-labelTreatment
Summary
This goal of this clinical trial is to evaluate how Acetadote affects metabolism in patients with glioblastoma. Drugs like Acetadote, which affect the level of damage in a cell (oxidative stress), may impact brain tumor metabolism and slow the growth of brain tumors. The investigators are evaluating how Acetadote affects glioblastoma metabolism by using MRI-based methods and by determining the changes in metabolism in brain tumor tissue resected from patients with a new diagnosis of glioblastoma.
Timeline
- Start
- 2026-06-18
- Primary completion
- 2027-07-01
- Completion
- 2028-07-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | N-acetylcysteine | Small molecule | 150 mg/kg | Intravenous |