drugset / Trial / NCT07393503

Musculoskeletal Outcomes Using Tylenol/Ibuprofen vs. Oral Steroids in New Injuries

NCT07393503

Phase 4 Enrolling by invitation 60 enrolled State University of New York at Buffalo
RandomizedSequentialSingle-blindOther

Summary

In this pilot study, the investigators aim to compare two short-term pain relief methods administered over the course of 6 days in the setting of acute musculoskeletal (MSK) pain: 1. Methylprednisolone((Medrol)dose pack- standard taper per dose pack instructions 2. Standard of Care (SOC) which includes a combination of Acetaminophen (Tylenol)+Ibuprofen (Motrin) The investigators are interested in studying pain relief regimens for acute injury of any body part among an adult orthopaedic urgent care population.

Timeline

Start
2025-09-17
Primary completion
2026-08
Completion
2027-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Acetaminophen Small molecule 1000 mg
Comparator Ibuprofen Small molecule 600 mg
Comparator Methylprednisolone Other / unclassified 4 mg