drugset / Trial / NCT07416474

RC148 Plus Platinum-Based Chemotherapy vs Tislelizumab Plus Platinum-Based Chemotherapy for First-Line Squamous Non-Small Cell Lung Cancer (sqNSCLC)

NCT07416474

Phase 3 Recruiting 574 enrolled RemeGen Co., Ltd.
RandomizedParallel-groupDouble-blindTreatment

Summary

This study aims to evaluate the efficacy and safety of RC148 combined with platinum-based chemotherapy versus Tislelizumab combined with platinum-based chemotherapy in participants with locally advanced or metastatic Squamous NSCLC who have not received first-line treatment. Participants will: Take RC148 or Tislelizumab combined with platinum-based chemotherapy until the end of the research.

Timeline

Start
2026-04-03
Primary completion
2027-12-31
Completion
2029-11-30

Drugs

EvaluationDrugModalityDoseRoute
Subject RC148 Unknown
Comparator Tislelizumab Monoclonal antibody
Comparator Carboplatin Small molecule
Comparator Paclitaxel Small molecule