drugset / Trial / NCT07420127

Comparison of Two Different Doses of Phenylephrine on Oxytocin Hemodynamic Effect

NCT07420127

Phase 4 Recruiting 112 enrolled Rawalpindi Medical College
RandomizedParallel-groupDouble-blindPrevention

Summary

Cesarean section is one of the commonly performed surgical procedures in the world. Once baby is delivered during the surgical procedure anesthesiologist administer Oxytocin drug through IV cannula which helps the Uterus to contract so that excessive blood loss doesnt occur. But this is associated with fall in blood pressure frequently requiring administration of medications to treat low blood pressure. The most frequently used drug is phenylephrine which can administered along with oxytocin to prevent fall in blood pressure. This study will compare to different doses of Phenylephrine to prevent fall in blood pressure.

Timeline

Start
2026-02-13
Primary completion
2026-07-13
Completion
2026-07-13

Publications

  • Background Sharma N, Agarwal S, Modi YC, Yadav A, Yadav J, Sindhi R, et al. Effect of Two Different Doses of Intravenous Phenylephrine on the Prevention of Oxytocin Induced Hypotension in Lower Segment Caesarean Section Under Subarachnoid Block: A Randomised Controlled Study. J Clin Diagn Res. 2023;17(9):16-21.

Drugs

EvaluationDrugModalityDoseRoute
Comparator Phenylephrine Small molecule 50 ug Intravenous
Comparator Phenylephrine Small molecule 75 ug Intravenous

Indications

No indication recorded.