drugset / Trial / NCT07420127
Comparison of Two Different Doses of Phenylephrine on Oxytocin Hemodynamic Effect
RandomizedParallel-groupDouble-blindPrevention
Summary
Cesarean section is one of the commonly performed surgical procedures in the world. Once baby is delivered during the surgical procedure anesthesiologist administer Oxytocin drug through IV cannula which helps the Uterus to contract so that excessive blood loss doesnt occur. But this is associated with fall in blood pressure frequently requiring administration of medications to treat low blood pressure. The most frequently used drug is phenylephrine which can administered along with oxytocin to prevent fall in blood pressure. This study will compare to different doses of Phenylephrine to prevent fall in blood pressure.
Timeline
- Start
- 2026-02-13
- Primary completion
- 2026-07-13
- Completion
- 2026-07-13
Publications
- Background Sharma N, Agarwal S, Modi YC, Yadav A, Yadav J, Sindhi R, et al. Effect of Two Different Doses of Intravenous Phenylephrine on the Prevention of Oxytocin Induced Hypotension in Lower Segment Caesarean Section Under Subarachnoid Block: A Randomised Controlled Study. J Clin Diagn Res. 2023;17(9):16-21.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Phenylephrine | Small molecule | 50 ug | Intravenous |
| Comparator | Phenylephrine | Small molecule | 75 ug | Intravenous |
Indications
No indication recorded.