drugset / Trial / NCT07433023

tSCS and 5-Azacitidine for Enhanced Motor Outcomes in Cerebral Palsy

NCT07433023 ↗

Phase 2 Recruiting 80 enrolled Shirley Ryan AbilityLab
RandomizedParallel-groupTriple-blindOther

Summary

This is an intervention study to investigate the impact of spinal stimulation on mobility outcomes in children with Cerebral Palsy. Participants will complete a 16-week training program with weekly sessions of spinal stimulation and walking or activity-based training. Participants will also have the option to participate in a randomized control trial to investigate the impact of 5-Azacitidine combined with the spinal stimulation to further affect mobility outcomes.

Timeline

Start
2026-05-28
Primary completion
2029-01-01
Completion
2029-01-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Azacitidine Other / unclassified 75 mg/m2 Subcutaneous

Indications