Perioperative Multimodal Analgesia for Supratentorial Craniotomy

Summary

This randomized clinical trial aims to evaluate the effectiveness of scalp nerve blocks and dexmedetomidine in reducing opioid use and preventing postoperative delirium in patients undergoing supratentorial brain tumor surgery. A total of 2000 patients will be randomly assigned to one of four groups, receiving either active treatments, placebos, or their combinations. The main outcome measured will be the amount of opioid pain medication needed after surgery.

Timeline

Start

2026-03-01

Primary completion

2027-12-31

Completion

2027-12-31

Drugs

Indications