drugset / Trial / NCT07449780

A Study of AK104 (SC) in Combination With Oxaliplatin and Capecitabine (XELOX) Versus AK104 (IV) in Combination With XELOX in Participants With Unresectable Locally Advanced or Metastatic Gastric Adenocarcinoma or Gastroesophageal Junction Adenocarcinoma

NCT07449780

Phase 3 Not yet recruiting 422 enrolled Akeso
RandomizedParallel-groupOpen-labelTreatment

Summary

A Study of AK104 (SC) in Combination With Oxaliplatin and Capecitabine (XELOX) Versus AK104 (IV) in Combination With XELOX in Participants With Unresectable Locally Advanced or Metastatic Gastric Adenocarcinoma or Gastroesophageal Junction Adenocarcinoma

Timeline

Start
2026-03-31
Primary completion
2027-11-17
Completion
2028-02-15

Drugs

EvaluationDrugModalityDoseRoute
Subject Cadonilimab Monoclonal antibody Subcutaneous
Background Capecitabine Small molecule Oral
Background Oxaliplatin Small molecule Intravenous