drugset / Trial / NCT07452198

A Study of GR1803 Injection Versus Daratumumab, Pomalidomide, and Dexamethasone (DPd) in Participants With Relapsed or Refractory Multiple Myeloma

NCT07452198

Phase 3 Recruiting 358 enrolled Genrix (Shanghai) Biopharmaceutical Co., Ltd.
RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to compare the efficacy of GR1803 Injection with daratumumab in combination with pomalidomide and dexamethasone (DPd).

Timeline

Start
2026-03-09
Primary completion
2029-03
Completion
2030-03

Drugs

EvaluationDrugModalityDoseRoute
Comparator Daratumumab Monoclonal antibody 1800 mg Subcutaneous
Subject GR1803 Unknown 180 ug/kg Intravenous
Comparator Dexamethasone Small molecule 20 mg
Comparator Dexamethasone Small molecule 40 mg
Comparator Pomalidomide Other / unclassified 4 mg

Indications