drugset / Trial / NCT07460050

Comparison of Two Sedative Agents in Terms of Controlled Hypotension

NCT07460050

Not yet recruiting 136 enrolled Hayatabad Medical Complex
RandomizedParallel-groupOpen-labelPrevention

Summary

Propofol and Isoflurane are commonly used sedative agents in general anaesthesia.Both these drugs have a side effect of decreasing blood pressure which when used optimally can be used to acheive controlled hypotention. So, it provides a better visiblity of surgical filed to the surgeons.This RCT compares propofol infusion vs isoflurane inhalation for inducing controlled hypotension during endoscopic sinus surgery. The goal is to assess which agent better controls blood pressure, improves surgical field visibility, and impacts recovery. It likely measures outcomes like hemodynamics, bleeding, and surgeon satisfaction.

Timeline

Start
2026-03-01
Primary completion
2026-08-01
Completion
2026-08-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Isoflurane Other / unclassified 1 % Inhaled
Comparator Isoflurane Other / unclassified 2 % Inhaled
Subject Propofol Small molecule 12 mg/kg

Indications

No indication recorded.