drugset / Trial / NCT07460050
Comparison of Two Sedative Agents in Terms of Controlled Hypotension
RandomizedParallel-groupOpen-labelPrevention
Summary
Propofol and Isoflurane are commonly used sedative agents in general anaesthesia.Both these drugs have a side effect of decreasing blood pressure which when used optimally can be used to acheive controlled hypotention. So, it provides a better visiblity of surgical filed to the surgeons.This RCT compares propofol infusion vs isoflurane inhalation for inducing controlled hypotension during endoscopic sinus surgery. The goal is to assess which agent better controls blood pressure, improves surgical field visibility, and impacts recovery. It likely measures outcomes like hemodynamics, bleeding, and surgeon satisfaction.
Timeline
- Start
- 2026-03-01
- Primary completion
- 2026-08-01
- Completion
- 2026-08-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Isoflurane | Other / unclassified | 1 % | Inhaled |
| Comparator | Isoflurane | Other / unclassified | 2 % | Inhaled |
| Subject | Propofol | Small molecule | 12 mg/kg | — |
Indications
No indication recorded.