drugset / Trial / NCT07464886
Prefrontal Glutamatergic Modulation by NAC and MBCT for Depression in Youth
Phase 3
Recruiting
160 enrolled
University of Cincinnati
National Center for Complementary and Integrative Health (NCCIH) · collab
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The primary goal is to investigate to what extent changes in glutamate and glutathione modulation and functional integration between brain networks associated with emotion and attention regulation are associated with treatment response in mildly depressed youth.
Timeline
- Start
- 2026-02-26
- Primary completion
- 2030-03
- Completion
- 2030-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | N-acetylcysteine | Small molecule | 2400 mg | — |