drugset / Trial / NCT07467603
ED50 of Remimazolam for Anesthesia Induction in Frail Elderly Patients
Non-randomizedParallel-groupOpen-labelTreatment
Summary
This study aimed to determine the median effective dose (ED50) of remimazolam for loss of consciousness (LOC) in elderly and frail elderly patients using the Dixon up-and-down method, while utilizing a novel Respiratory Volume Monitor (RVM) to detect subclinical respiratory depression.
Timeline
- Start
- 2025-02-01
- Primary completion
- 2025-04-30
- Completion
- 2025-04-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Remimazolam | Small molecule | 0.13 mg/kg | Intravenous |
| Subject | Remimazolam | Small molecule | 0.15 mg/kg | Intravenous |
Indications
No indication recorded.