drugset / Trial / NCT07467603

ED50 of Remimazolam for Anesthesia Induction in Frail Elderly Patients

NCT07467603

Non-randomizedParallel-groupOpen-labelTreatment

Summary

This study aimed to determine the median effective dose (ED50) of remimazolam for loss of consciousness (LOC) in elderly and frail elderly patients using the Dixon up-and-down method, while utilizing a novel Respiratory Volume Monitor (RVM) to detect subclinical respiratory depression.

Timeline

Start
2025-02-01
Primary completion
2025-04-30
Completion
2025-04-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Remimazolam Small molecule 0.13 mg/kg Intravenous
Subject Remimazolam Small molecule 0.15 mg/kg Intravenous

Indications

No indication recorded.