drugset / Trial / NCT07472153

PD-1 (Programmed Death-1) Versus PD-L1 (Programmed Death-ligand 1) Immune Check Point Inhibitors Combined With Chemotherapy, With or Without Bevacizumab, In Patients With Metastatic, Persistent Or Recurrent Cervical Cancer

NCT07472153

Phase 2/3 Recruiting 120 enrolled N.N. Alexandrov National Cancer Centre
RandomizedParallel-groupSingle-blindTreatment

Summary

This is a randomized trial evaluating the results of using of PD-1 and PD-L1 immune checkpoint inhibitors combined with chemotherapy, with or without bevacizumab, in patients with metastatic, persistent, and recurrent cervical cancer.

Timeline

Start
2025-07-01
Primary completion
2030-06-30
Completion
2033-06-30

Drugs

EvaluationDrugModalityDoseRoute
Comparator Bevacizumab Monoclonal antibody
Comparator Carboplatin Small molecule
Comparator Cisplatin Other / unclassified 75 mg/m2
Comparator Paclitaxel Small molecule 175 mg/m2

Indications