drugset / Trial / NCT07480785
TEAS Combined With Triple Antiemetic Drugs to Prevent PONV in High-Risk Patients
Recruiting
780 enrolled
Zhejiang University
Huzhou Central Hospital · collabJinhua Central Hospital · collabThe First People's Hospital of Huzhou · collab
RandomizedParallel-groupDouble-blindPrevention
Summary
The goal of this clinical trial is to evaluate the effects of transcutaneous electrical acupoint stimulation (TEAS) combined with triple antiemetics for postoperative nausea and vomiting (PONV) in high-risk patients. The primary question it seeks to answer is: Does TEAS combined with triple antiemetics further reduce the incidence of PONV in high-risk subjects? Researchers will compare active TEAS with sham stimulation to determine whether the addition of TEAS to dexamethasone, palonosetron, and droperidol lowers the PONV rate beyond that achieved by the triple-drug prophylaxis alone.
Timeline
- Start
- 2026-01-16
- Primary completion
- 2027-10-31
- Completion
- 2027-10-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Background | Dexamethasone | Small molecule | 5 mg | Intravenous |
| Background | Droperidol | Small molecule | 1.25 mg | Intravenous |
| Background | Palonosetron | Other / unclassified | 0.25 mg | Intravenous |