drugset / Trial / NCT07489586

A Clinical Study of QL1207H Injection Versus Aflibercept for Neovascular Age-related Macular Degeneration

NCT07489586

Phase 3 Not yet recruiting 356 enrolled Qilu Pharmaceutical Co., Ltd.
RandomizedParallel-groupTriple-blindTreatment

Summary

The goal of this clinical trial is to evaluate the efficacy and safety of QL1207H injection versus aflibercept 8 mg in patients with neovascular age-related macular degeneration. The main question it aims to answer is: • Whether the efficacy and safety of QL1207H and aflibercept 8 mg are similar. Participants will receive injection once every 4 weeks for 3 consecutive doses, followed by injection once every 16 weeks at maximum. Researchers will compare QL1207H group and aflibercept 8 mg group to see if they are similar in improving best corrected visual acuity.

Timeline

Start
2026-03
Primary completion
2026-12
Completion
2027-08

Drugs

EvaluationDrugModalityDoseRoute
Comparator Aflibercept Protein / enzyme biologic 8 mg
Subject QL1207H Unknown