drugset / Trial / NCT07489924
Microbiological Effect of 0.12% Chlorhexidine Digluconate and 0.05% Cetylpyridinium Chloride vs Probiotics (Lactobacillus Reuteri Prodentis) on Porphyromonas Gingivalis.
RandomizedParallel-groupSingle-blindTreatment
Summary
This randomized non-inferiority clinical trial aims to evaluate the microbiological effect of 0.12% chlorhexidine and 0.05% cetylpyridinium vs. probiotics (Lactobacillus reuteri Prodentis) on Porphyromonas gingivalis in patients with periodontal disease and diabetes mellitus in Colima, where molecular biology tests such as qPCR will be performed at the end, before and after treatment in each of the groups.
Timeline
- Start
- 2023-01-08
- Primary completion
- 2025-07-31
- Completion
- 2026-07-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Cetylpyridinium | Small molecule | 0.05 % | Oral |
| Comparator | Chlorhexidine gluconate | Other / unclassified | 0.12 % | Oral |
| Subject | Lactobacillus reuteri Prodentis | Other / unclassified | — | Oral |