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drugset / Trial / NCT07491146

Phase II Clinical Study of the Efficacy and Safety of HSK55718 in the Treatment of Abdominal Postoperative Pain

NCT07491146 ↗

Phase 2 Not yet recruiting 200 enrolled Yingyong Zhou,MD,PhD
RandomizedParallel-groupQuadruple-blindTreatment

Summary

A multicenter, randomized, double-blind, placebo-controlled, and positive-controlled phase II clinical trial was conducted to evaluate the efficacy and safety of HSK55718 injection for postoperative analgesia in patients undergoing abdominal surgery. The primary objective was to evaluate the efficacy of HSK55718 for postoperative analgesia after abdominal surgery. The secondary objective was to evaluate the safety and pharmacokinetic profile of TRD303 solution for postoperative analgesia after abdominal surgery.

Timeline

Start
2026-03-25
Primary completion
2026-10-30
Completion
2026-12-30

Drugs

EvaluationDrugModalityDoseRoute
Subject HSK55718 Unknown 7.5 mg Intravenous
Subject HSK55718 Unknown 30 mg Intravenous
Subject HSK55718 Unknown 60 mg Intravenous
Comparator Morphine Other / unclassified 2 mg Intravenous

Indications

No indication recorded.