drugset / Trial / NCT07494136

Dose Dependent Steroid Injections

NCT07494136

Phase 4 Not yet recruiting 150 enrolled University of Miami
RandomizedParallel-groupSingle-blindTreatment

Summary

This study aims to evaluate the efficacy of interlaminar steroid injections at treating pain in lumbar radiculopathy at varying doses, to evaluate the efficacy of interlaminar steroid injections at improving quality of life and function in lumbar radiculopathy at varying doses, and to evaluate difference in efficacy between triamcinolone and dexamethasone interlaminar steroid injections at treating pain in lumbar radiculopathy at varying doses, with the overarching hypotheses that there is no difference in reported pain reduction, quality of life, or function among patients receiving low, moderate, or high doses, and no difference in reported pain reduction between triamcinolone and dexamethasone.

Timeline

Start
2026-05
Primary completion
2027-05
Completion
2027-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Dexamethasone Small molecule 2 mg Other
Subject Dexamethasone Small molecule 4 mg Other
Subject Dexamethasone Small molecule 8 mg Other
Subject Triamcinolone Other / unclassified 10 mg Other
Subject Triamcinolone Other / unclassified 40 mg Other
Subject Triamcinolone Other / unclassified 80 mg Other

Indications