drugset / Trial / NCT07494435
Phase 2 Study of WGI-0301 Plus Nivolumab in Patients With HCC and RCC
RandomizedParallel-groupOpen-labelTreatment
Summary
This is a Phase II study being done at several hospitals without using a placebo. It will look at how safe and tolerable the drug WGI-0301 is when given together with nivolumab, how the body processes and responds to WGI-0301, and whether this combination shows early signs of working in people with advanced liver cancer or advanced kidney cancer.
Timeline
- Start
- 2026-06-01
- Primary completion
- 2028-06-01
- Completion
- 2028-09-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Nivolumab | Monoclonal antibody | 240 mg | Intravenous |
| Subject | WGI-0301 | Antisense oligonucleotide | — | — |