drugset / Trial / NCT07494435

Phase 2 Study of WGI-0301 Plus Nivolumab in Patients With HCC and RCC

NCT07494435

Phase 2 Not yet recruiting 230 enrolled Zhejiang Haichang Biotech Co., Ltd.
RandomizedParallel-groupOpen-labelTreatment

Summary

This is a Phase II study being done at several hospitals without using a placebo. It will look at how safe and tolerable the drug WGI-0301 is when given together with nivolumab, how the body processes and responds to WGI-0301, and whether this combination shows early signs of working in people with advanced liver cancer or advanced kidney cancer.

Timeline

Start
2026-06-01
Primary completion
2028-06-01
Completion
2028-09-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Nivolumab Monoclonal antibody 240 mg Intravenous
Subject WGI-0301 Antisense oligonucleotide