drugset / Trial / NCT07497568

Effect of Local Application of 1% Metformin Gel on Implant Stability and Peri-implant Bone Density: A Randomized Controlled Study

NCT07497568

Recruiting 34 enrolled University of Baghdad
RandomizedParallel-groupOpen-labelTreatment

Summary

This randomized controlled clinical study aims to evaluate the effect of local application of 1% metformin gel on implant stability and peri-implant bone density. Patients requiring dental implants will be randomly allocated into two groups: a control group and a test group receiving metformin gel. Implant stability will be assessed using resonance frequency analysis, and bone density will be evaluated using CBCT imaging. The outcomes will be compared over a follow-up period to determine the effectiveness of metformin in enhancing osseointegration

Timeline

Start
2025-11-01
Primary completion
2027-03-09
Completion
2027-06-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Metformin Small molecule 1 % Other

Indications

No indication recorded.