Decontamination Methods in the Treatment of Peri-implantitis
Summary
The goal of this clinical study is to compare the effectiveness of different methods for decontaminating dental implant surfaces in the treatment of peri-implantitis. The main question it aims to answer is: Which combination of an antiseptic solution and an air-polishing powder is most effective for the non-surgical treatment of peri-implantitis? Researchers will compare three different treatment combinations (Miramistin with sodium bicarbonate, chlorhexidine with erythritol, and Octenisept with glycine) in patients diagnosed with peri-implantitis. Participants will receive the combined treatment at intervals of 7-10 days for one month. The study will assess changes in probing depth, bleeding, and bone loss at 1 and 2.5 months after treatment to determine the most effective and balanced approach for preserving implant surfaces and promoting tissue healing.
Timeline
- Start
- 2023-02-01
- Primary completion
- 2025-11-30
- Completion
- 2025-12-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Benzyl-dimethyl-[3-(tetradecanoylamino)propyl]azanium | Small molecule | 0.01 % | — |
| Comparator | Chlorhexidine | Small molecule | 0.05 % | — |
| Comparator | Octenisept | Unknown | — | — |