drugset / Trial / NCT07500844

Decontamination Methods in the Treatment of Peri-implantitis

NCT07500844

Non-randomizedParallel-groupSingle-blindTreatment

Summary

The goal of this clinical study is to compare the effectiveness of different methods for decontaminating dental implant surfaces in the treatment of peri-implantitis. The main question it aims to answer is: Which combination of an antiseptic solution and an air-polishing powder is most effective for the non-surgical treatment of peri-implantitis? Researchers will compare three different treatment combinations (Miramistin with sodium bicarbonate, chlorhexidine with erythritol, and Octenisept with glycine) in patients diagnosed with peri-implantitis. Participants will receive the combined treatment at intervals of 7-10 days for one month. The study will assess changes in probing depth, bleeding, and bone loss at 1 and 2.5 months after treatment to determine the most effective and balanced approach for preserving implant surfaces and promoting tissue healing.

Timeline

Start
2023-02-01
Primary completion
2025-11-30
Completion
2025-12-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Benzyl-dimethyl-[3-(tetradecanoylamino)propyl]azanium Small molecule 0.01 %
Comparator Chlorhexidine Small molecule 0.05 %
Comparator Octenisept Unknown

Indications