drugset / Trial / NCT07508995

A Phase 2 Trial Of The Bruton Tyrosine Kinase Degrader BGB-16673 In Combination With BCL-2 Inhibitor Sonrotoclax For Patients With Treatment-Naive Chronic Lymphocytic Leukemia (CLL)

NCT07508995

Phase 2 Not yet recruiting 40 enrolled M.D. Anderson Cancer Center
NaSingle-groupOpen-labelTreatment

Summary

This is an open-label, single-arm, phase II study which will assess the safety and efficacy of BGB16673 in combination with sonrotoclax as a time-limited approach for participants with treatment-naive CLL/SLL.

Timeline

Start
2026-09-01
Primary completion
2031-07-01
Completion
2033-07-01

Drugs

EvaluationDrugModalityDoseRoute
Subject BGB-16673 Other / unclassified Oral
Subject Sonrotoclax Other / unclassified Oral