drugset / Trial / NCT07520760

A Multicenter, Single-Arm, Phase II Exploratory Study of Eribulin in Combination With Anlotinib for HER2-Negative Recurrent/Metastatic Breast Cancer Previously Treated With Antibody-Drug Conjugates

NCT07520760

Phase 2 Recruiting 52 enrolled Sun Yat-sen University
NaSingle-groupOpen-labelTreatment

Summary

This study is looking at a new combination of two drugs-eribulin and anlotinib-for patients with HER2-negative advanced breast cancer. Participants in this study have already tried other treatments like T-DXd or SG, but their cancer has gotten worse, and there are currently no standard treatment options left for them. Researchers believe that using these two drugs together may work better than using either one alone based on how they target cancer cells. The goal is to offer a new choice and help improve survival for these patients.

Timeline

Start
2026-04-01
Primary completion
2030-04-30
Completion
2035-04-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Catequentinib Small molecule 8 mg Oral
Subject Eribulin Small molecule 1.4 mg/m2 Intravenous