drugset / Trial / NCT07541456

Empagliflozin Versus Non-SGLT2 Oral Drugs for Blood Pressure in Type 2 Diabetes

NCT07541456

Phase 4 Completed 300 enrolled Dr. Zarmina Younes
RandomizedParallel-groupSingle-blindTreatment

Summary

This randomized controlled trial studied whether empagliflozin lowers blood pressure better than non-SGLT2 oral hypoglycemic treatment in adults with type 2 diabetes mellitus and hypertension. A total of 300 participants were assigned to 1 of 2 treatment groups and followed for 12 weeks. One group received empagliflozin and the other received non-SGLT2 oral therapy. Blood pressure was measured at baseline and again after 12 weeks to compare the effect of treatment on systolic and diastolic blood pressure.

Timeline

Start
2025-06-09
Primary completion
2025-11-08
Completion
2025-11-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Empagliflozin Small molecule 25 mg
Comparator Metformin Small molecule 500 mg