drugset / Trial / NCT07548255

The Efficacy and Safety of Sonrotoclax, Zanubrutinib Combined With Obinutuzumab in MCL

NCT07548255

Phase 1 Not yet recruiting 28 enrolled Ruijin Hospital
NaSingle-groupOpen-labelTreatment

Summary

A Single-Arm, Prospective Clinical Study Evaluating the Efficacy and Safety of Sonrotoclax, Zanubrutinib Combined with Obinutuzumab in the First-Line Treatment of Newly Diagnosed Intermediate-to-High-Risk Mantle Cell Lymphoma

Timeline

Start
2026-04-20
Primary completion
2029-03-01
Completion
2029-03-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Obinutuzumab Monoclonal antibody 1000 mg Intravenous
Subject Sonrotoclax Other / unclassified 320 mg
Subject Zanubrutinib Small molecule 160 mg

Indications