drugset / Trial / NCT07597902

SARS-CoV-2 and Herpesvirus Inhibition for Ending Long COVID Dysfunction

NCT07597902

Phase 2 Not yet recruiting 150 enrolled Icahn School of Medicine at Mount Sinai
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The purpose of this research study is to test if the combination of three drugs, valacyclovir, celecoxib, and Paxlovid will decrease the symptoms of Long COVID in adults compared to a placebo (this does not contain the medications).

Timeline

Start
2026-06-01
Primary completion
2028-06-30
Completion
2028-06-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Celecoxib Other / unclassified 200 mg Oral
Subject Nirmatrelvir Small molecule 150 mg Oral
Subject Ritonavir Other / unclassified 100 mg Oral
Subject Valacyclovir Unknown 1500 mg Oral

Indications