drugset / Trial / NCT07603375

Upfront Chemotherapy With Radiation Therapy (CRT) Followed by Chemotherapy in Localized Esophageal Adenocarcinoma

NCT07603375

Phase 2 Not yet recruiting 60 enrolled Duke University
NaSingle-groupOpen-labelTreatment

Summary

The goal of this trial is to learn if adding consolidative chemotherapy to routine chemoradiation can better control both local recurrence and metastasis and reduce the need for surgical intervention.

Timeline

Start
2026-08-01
Primary completion
2029-08-01
Completion
2034-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Docetaxel Small molecule
Subject Leucovorin Small molecule
Subject Oxaliplatin Small molecule
Subject fluorouracil Small molecule