drugset / Trial / NCT07611344
The Effect of Remimazolam Versus Propofol on Postoperative Extubation Time
RandomizedParallel-groupTriple-blindOther
Summary
This clinical trial aims to help us understand how two drugs, Propofol and Remazoloam, affect when researchers remove a Participants' breathing tube after liver surgery (laparoscopic liver resection).The main research questions include: comparing the time to breathing tube removal between patients who receive each drug, comparing changes in heart rate and blood pressure during surgery, and comparing the rates of unwanted medical events after surgery. Researchers will give either Propofol or Remimazolam as a sedative medicine for anesthesia. This will allow the researchers to compare the time to breathing tube removal after surgery. Participants will complete their surgery according to a pre-planned surgical plan.
Timeline
- Start
- 2026-05-31
- Primary completion
- 2026-12-01
- Completion
- 2026-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Propofol | Small molecule | 4 mg/kg | Intravenous |
| Comparator | Propofol | Small molecule | 10 mg/kg | Intravenous |
| Subject | Remimazolam | Small molecule | 0.4 mg/kg | Intravenous |
| Subject | Remimazolam | Small molecule | 0.7 mg/kg | Intravenous |
Indications
No indication recorded.