drugset / Trial / NCT07612631
Imaging CRF X NOP Interactions in Alcohol Use Disorder
Phase 0
Recruiting
90 enrolled
Rajesh Narendran
National Institute on Alcohol Abuse and Alcoholism (NIAAA) · collab
NaSingle-groupOpen-labelBasic science
Summary
This positron emission tomography imaging study uses \[C-11\]NOP-1A and hydrocortisone to image stress-modulating proteins in heavy drinking alcohol use disorder (AUD) subjects and healthy controls (HC). It will also characterize the role of these stress-regulating proteins in a relapse to alcohol.
Timeline
- Start
- 2026-06-01
- Primary completion
- 2031-06-30
- Completion
- 2032-06-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Hydrocortisone | Other / unclassified | 1 mg/kg | Intravenous |