drugset / Trial / NCT07614828

Exploratory Clinical Study of Neoadjuvant Immunotherapy Combined With Chemotherapy in Malignant Melanoma of Nasal and Paranasal Mucosa

NCT07614828 ↗

NaSingle-groupOpen-labelTreatment

Summary

Sinonasal mucosal malignant melanoma (SNMM) is a nasal and paranasal sinus malignancy with a low incidence and extremely poor prognosis, exhibiting specificity in Asian populations. For resectable SNMM, the efficacy of neoadjuvant immunotherapy is unclear. This prospective clinical study aims to explore the survival prognosis of neoadjuvant immunotherapy combing radiochemotherapy after Endoscopic Surgery for resectable SNMM.

Timeline

Start
2023-06-01
Primary completion
2026-06-30
Completion
2026-06-30

Outcome

Outcome not reported

Stopped (Enrollment): “no participants enrolled”

Drugs

EvaluationDrugModalityDoseRoute
Subject Temozolomide Small molecule — —
Subject Toripalimab Monoclonal antibody — —

Indications