drugset / Trial / NCT07618182

Effect of Two Different Concentrations of Sodium Hypochlorite on Post-Operative Pain Following Single-Visit Root Canal Treatment

NCT07618182

Not yet recruiting 116 enrolled College of Physicians and Surgeons Pakistan
RandomizedParallel-groupSingle-blindTreatment

Summary

This randomized controlled trial aims to evaluate the effect of two different concentrations of sodium hypochlorite (2.5% and 5.25%) on post-operative pain following single-visit root canal treatment. A total of 116 participants requiring primary endodontic treatment will be randomly allocated into two groups according to irrigant concentration. Post-operative pain will be assessed using a 100-mm Visual Analog Scale at 6, 12, 24, and 48 hours after treatment. The study seeks to determine the concentration that provides optimal disinfection with minimal patient discomfort.

Timeline

Start
2026-07-05
Primary completion
2026-12-05
Completion
2026-12-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Sodium Hypochlorite Unknown 2.5 % Other
Subject Sodium Hypochlorite Unknown 5.25 % Other

Indications

No indication recorded.