drugset / Trial / NCT07618182
Effect of Two Different Concentrations of Sodium Hypochlorite on Post-Operative Pain Following Single-Visit Root Canal Treatment
RandomizedParallel-groupSingle-blindTreatment
Summary
This randomized controlled trial aims to evaluate the effect of two different concentrations of sodium hypochlorite (2.5% and 5.25%) on post-operative pain following single-visit root canal treatment. A total of 116 participants requiring primary endodontic treatment will be randomly allocated into two groups according to irrigant concentration. Post-operative pain will be assessed using a 100-mm Visual Analog Scale at 6, 12, 24, and 48 hours after treatment. The study seeks to determine the concentration that provides optimal disinfection with minimal patient discomfort.
Timeline
- Start
- 2026-07-05
- Primary completion
- 2026-12-05
- Completion
- 2026-12-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Sodium Hypochlorite | Unknown | 2.5 % | Other |
| Subject | Sodium Hypochlorite | Unknown | 5.25 % | Other |
Indications
No indication recorded.