drugset / Trial / NCT07623200

A Phase 3 Study of INCA033989 Versus Best Available Therapy in Participants With Essential Thrombocythemia

NCT07623200

Phase 3 Not yet recruiting 426 enrolled Incyte Corporation
RandomizedParallel-groupOpen-labelTreatment

Summary

This study is being conducted to evaluate INCA033989 versus best available therapy in participants with essential thrombocythemia and a CALR mutation previously treated with cytoreductive therapy.

Timeline

Start
2026-07-31
Primary completion
2029-06-15
Completion
2030-11-01

Drugs

EvaluationDrugModalityDoseRoute
Subject ANA Unknown
Subject INCA033989 Unknown Intravenous
Subject Peginterferon alfa-2a Protein / enzyme biologic
Subject Ropeginterferon alfa-2b Protein / enzyme biologic