drugset / Trial / NCT07637279

Patient Controlled Propofol Sedation Versus Standard Sedation in Advanced Therapeutic Colonoscopy With a Focus on Patient Satisfaction

NCT07637279

RandomizedParallel-groupOpen-labelHealth-services research

Summary

The goal of this clinical trial is to learn if patient administered propofol sedation results in superior patient satisfaction compared to standard conscious sedation in advanced therapeutic endoscopy. • Does self administration of the sedative propofol increase patient satisfaction? Researchers will compare patient administered propofol sedation (where the patient administers propofol by pushing a button) with standard conscious sedation Participants will: * Be randomized to either sedation route. * Answer a preendoscopy questioneere and a postendoscopy questioneere 1 hour after the examination as well as one week after the examination.

Timeline

Start
2026-11-01
Primary completion
2028-06-15
Completion
2028-11-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Fentanyl Other / unclassified 0.25 mg Intravenous
Comparator Fentanyl Other / unclassified 0.5 mg Intravenous
Comparator Midazolam Small molecule 1 mg Intravenous
Comparator Midazolam Small molecule 2 mg Intravenous
Subject Propofol Small molecule 5 mg Intravenous