drugset / Trial / NCT07637968
Tegileridine vs Sufentanil for Postoperative Pain Management and Gastrointestinal Recovery After Major Laparoscopic Abdominal Surgery
Phase 4
Not yet recruiting
84 enrolled
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
RandomizedParallel-groupTriple-blindTreatment
Summary
This study is a single-center, randomized, triple-blind clinical trial designed to compare tegileridine and sufentanil for postoperative analgesia and gastrointestinal tolerability in patients undergoing major laparoscopic abdominal surgery. Participants will be randomly assigned to receive either tegileridine or sufentanil for postoperative patient-controlled intravenous analgesia according to the study protocol. The purpose of this study is to determine whether tegileridine can provide better gastrointestinal tolerability while maintaining non-inferior postoperative pain control compared with sufentanil in this patient population.
Timeline
- Start
- 2026-06-01
- Primary completion
- 2027-01-01
- Completion
- 2027-06-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Sufentanil | Other / unclassified | 100 ug | Intravenous |
| Subject | Tegileridine | Small molecule | 5 mg | Intravenous |
| Background | Palonosetron | Other / unclassified | 0.5 mg | Intravenous |
Indications
No indication recorded.