drugset / Trial / NCT07638631

Ipilimumab (N01) Plus Sintilimab and Modified XELOX as Conversion Therapy in Unresectable Locally Advanced Gastric Cancer

NCT07638631

Phase 2 Not yet recruiting 30 enrolled Chen Lizhu
NaSingle-groupOpen-labelTreatment

Summary

This study was a prospective, single-arm, multi-center, phase Ⅱ clinical study to investigate the efficacy and safety of ipilimumab injection N01 combined with sintilimab and modified XELOX conversion therapy in patients with unresectable locally advanced gastric cancer who had not received systemic treatment.

Timeline

Start
2026-06-15
Primary completion
2028-12-31
Completion
2030-06-15

Drugs

EvaluationDrugModalityDoseRoute
Subject Capecitabine Small molecule 600 mg/m2
Subject Ipilimumab Monoclonal antibody
Subject Oxaliplatin Small molecule 78 mg/m2
Subject Sintilimab Monoclonal antibody

Indications