drugset / Trial / NCT07671378
A Study of MRD-Guided Zanubrutinib Plus Sonrotoclax in Treatment-Naïve, High-Risk CLL/SLL Patients
NaSingle-groupOpen-labelTreatment
Summary
This study is a prospective, multicenter, open-label, single-arm phase II clinical trial evaluating the efficacy and safety of an MRD-guided, time-limited therapy with zanubrutinib combined with sonrotoclax in previously untreated high-risk CLL/SLL patients.
Timeline
- Start
- 2026-06-01
- Primary completion
- 2027-12-31
- Completion
- 2030-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Sonrotoclax | Other / unclassified | 320 mg | Oral |
| Subject | Zanubrutinib | Small molecule | 160 mg | Oral |