Intraoperative Intravenous Lidocaine for Pain After Laparoscopic Appendectomy

Phase 4 Completed 225 enrolled Hospital Universitario de Caracas

RandomizedParallel-groupQuadruple-blindTreatment

Summary

This randomized, double-blind, placebo-controlled clinical trial evaluated whether intraoperative intravenous lidocaine infusion improves postoperative analgesia and recovery in patients undergoing laparoscopic appendectomy. The primary objective was to assess postoperative pain intensity and opioid consumption. Secondary outcomes included postoperative nausea and vomiting, time to bowel function recovery, length of hospital stay, plasma lidocaine concentrations, and adverse events.

Timeline

Start: 2024-02-01
Primary completion: 2025-01-01
Completion: 2025-01-01

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Lidocaine	Other / unclassified	—	Intravenous

Indications

No indication recorded.