drugset / Trial / NCT07687914

A Study of IMM2510 + IMM27M Combination Therapy in Patients With Advanced Hepatocellular Carcinoma

NCT07687914

Phase 2 Not yet recruiting 50 enrolled ImmuneOnco Biopharmaceuticals (Shanghai) Inc.
NaSingle-groupOpen-labelTreatment

Summary

This is a Phase 2, open-label, multicenter,study designed to evaluate the safety, tolerability, pharmacokinetics, and preliminary antitumor activity of IMM2510(Anti-PD-L1 and VEGF trap recombinant - Page 1 of 5 - protein) combine with IMM27M(Anti-CTLA-4 Humanized monoclonal antibody) in patients with advanced hepatocellular carcinoma who not have received the treatment for aHCC in past

Timeline

Start
2026-07-23
Primary completion
2027-07-23
Completion
2028-07-23

Drugs

EvaluationDrugModalityDoseRoute
Subject IMM27M Monoclonal antibody 1 mg/kg Intravenous
Subject PALVERAFUSP ALFA Protein / enzyme biologic 20 mg/kg Intravenous